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HBV Poster AASLD2016
STG-175 Paper on PLOS ONE, 2016
HCV Poster EASL2016
HCV Poster AASLD2015


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September of 2014
Sept. 9, 2014 (GLOBE NEWSWIRE)--OnCore Biopharma, Inc. ("OnCore" or the "Company"), a biotechnology company focused on the research, development and commercialization of oral treatments for chronic hepatitis B virus (HBV) infection, announced today the exclusive worldwide license to a series of second-generation cyclophilin inhibitors for the treatment of HBV from NeuroVive Pharmaceutical AB ("NeuroVive"; STO:NVP), a leading mitochondrial medicine company located in Lund, Sweden. Under the terms of the agreement, OnCore will pay NeuroVive an initial upfront payment, development and sales milestones, and royalties based on future sales. The total value of the license agreement is up to $150 million, excluding royalty payments.


July of 2014
Gilead's Hepatitis C Drug, Sovaldi, is on Pace to Become a Blockbuster
By Andrew Pollack, July 23, 2014, The New York Time

Sales of the new hepatitis C drug, Sovaldi, reached $3.5 billion in the second quarter, a huge figure that puts it on track to become one of the world's best-selling medicines but could intensify concerns about society's ability to pay for it. The sales, announced on Wednesday by Gilead Sciences, were an increase from the $2.3 billion in the first three months of the year, the first full quarter of sales since the drug's approval in December of 2013, Sovaldi, which costs $1,000 a pill or $84,000 for a typical 12-week course of treatment, is priced almost as high as drugs for rare diseases, even though more than three million Americans have hepatitis C.


June of 2014
The Combination of Alisporivir plus an NS5A Inhibitor Provides Additive to Synergistic Anti-Hepatitis C Virus Activity without Detectable Cross-Resistance.
Chatterji et al., Antimicrob. Agents Chemother. 2014, 58(6), 3327-3334.


May of 2014
1, Our HBV vaccine study has been initiated with novel concept and designing.
2, NVP018, A Cyclophilin Inhibitor for Treatment of Chronic HBV Infection
Nilsson et al., J. Hepatology 2014, 60(1) S423.
3, Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter NTCP.
Watashi et al., Hepatology 2014, 59:5, 1726-1737.


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